Drug - Zyflo® CR (zileuton) [Critical Therapeutics]
March 2008
Therapeutic Area - Asthma
Zyflo CR is a leukotriene synthesis inhibitor indicated for the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older.
Cases of severe hepatic injury have been reported in patients taking zileuton immediate release tablets. These cases included death, life-threatening liver injury with recovery, symptomatic jaundice, hyperbilirubinemia and elevations of ALT>8 times upper limits of normal.
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