Drug - Kynamro™ [Genezyme Corporation]
October 2013
Therapeutic area - Cardiovascular
Dose is 200 mg once weekly as a subcutaneous injection; quantity limit is 4 ml per 34-day supply.
KYNAMRO™ is an oligonucleotide inhibitor of apolipoprotein B-100 synthesis indicated as an adjunct to lipid-lowering medications and diet to reduce low density lipoprotein-cholesterol (LDL-C), apolipoprotein B (apo B), total cholesterol (TC), and non-high density lipoprotein-cholesterol (non HDL-C) in patients with homozygous familial hypercholesterolemia (HoFH).
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