Lotronex
Drug - Lotronex (alosetron hydrochloride) Tablets
October 2012
Therapeutic area - Irritable Bowel Syndrome (IBS), females only
Approval criteria
- Female recipient 18 years of age or older - with severe diarrhea* - predominant irritable bowel syndrome (IBS) AND
- Chronic IBS symptoms (generally lasting 6 months or longer) AND
- The physician excluded anatomical or biochemical abnormalities of the gastrointestinal tract AND
- Patient has not responded adequately to at least two drugs considered to be conventional therapy [e.g., dicyclomine, hyoscyamine, loperamide, diphenoxylate/atropine, fiber supplementation] for IBS AND
- The physician is enrolled in the Lotronex Prescribing Program
*Accepted definition of severe IBS includes diarrhea and 1 or more of the following:
- Frequent and severe abdominal pain or discomfort
- Frequent bowel urgency or fecal incontinence
- Disability or restriction of daily activities due to IBS
Questions?
MHCP Provider Call Center 651-431-2700 or 800-366-5411